Search on: INSULIN-LIKE GROWTH FACTOR RECEPTOR 
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Descriptor English:   Receptors, Somatomedin 
Descriptor Spanish:   Receptores de Somatomedina 
Descriptor Portuguese:   Receptores de Somatomedina 
Synonyms English:   Insulin-Like Growth Factor Receptor
Insulin-Like Growth Factor Receptors
Somatomedin Receptor
Insulin Like Growth Factor Receptor
Insulin Like Growth Factor Receptors
Receptor, Somatomedin
Receptors, Insulin Like Growth Factors
Receptors, Insulin-Like Growth Factors
Somatomedin Receptors  
Tree Number:   D12.776.543.750.750.400.780
Definition English:   Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes. 
Indexing Annotation English:   specifics are also available; DF: RECEPT SOMATOMEDIN
History Note English:   93; was INSULIN-LIKE GROWTH FACTOR RECEPTOR (NM) 1980-92; INSULIN-LIKE GROWTH FACTORS RECEPTORS was see RECEPTORS, SOMATOMEDIN 1993 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   30545 
Unique Identifier:   D017451 

Occurrence in VHL:
 

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